Alternative Molecular Tests for Virological Diagnosis

Assessment of Immunology Tests for Pregnancy Diagnosis

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Limits of commercial molecular tests for diagnosis of pulmonary tuberculosis.

Several studies report high specificity, but variable sensitivity, of Amplified Mycobacterium tuberculosis Direct Test (AMTDT, Gen-Probe) based on ribosomal ribonucleic acid (rRNA) amplification and Amplicor Mycobacterium tuberculosis test (Amplicor, Roche) based on deoxyribonucleic acid (DNA) amplification for diagnosis of pulmonary tuberculosis. We have retrospectively evaluated these assays ...

Evaluation of molecular tests for prenatal diagnosis of chromosome abnormalities.

improving urine sample efficacy as a convenient alternative for invasive samples in molecular diagnosis of toxoplasmosis.

background: diagnosis of some diseases is difficult due to invasive sampling. urine has been candi-date as a non-invasive and convenient alternative. it has many advantages and easy accessibility but some technical ills should be removed. finding a suitable extraction method for improving urine dna quantity and quality in altering invasive specimens for molecular diagnosis of some infectious di...

Virological diagnosis of Ebolavirus infection

Ebolaviruses, and the other viral causes of haemorrhagic fevers (VHF) have always posed special problems for diagnostic laboratories. These arise from the rarity of human infections, minimal documented experience with test delivery and interpretation, the paucity of established commercial or in-house assays, the lack of clinical material for test development and validation, the high level conta...